New controlled release systems produced by self-assembly of biopolymers and colloidal particles at fluid-fluid interfaces

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LMC Sagis, R de Ruiter, FJR Miranda, J de Ruiter, K Schroen, AC van Aelst, H Kieft, R Boom, E van der Linden, Polymer microcapsules with a fiber-reinforced nanocomposite shell LANGMUIR 24 (2008) 1608 ► Polymer microcapsules can be used as controlled release systems in drugs or in foods. Using layer-by-layer adsorption of common food proteins and polysaccharides, we produced a new type of microcapsule with tunable strength and permeability. The shell consists of alternating layers of pectin and whey protein fibrils, yielding a fiber-reinforced nanocomposite shell. The strength can be tightly controlled by varying the number of layers or the density and length of the fibrils in the protein layers. The mechanical stability of these microcapsules appears to be superior to that of currently available multilayer capsules. The method involves only standard unit operations and has the potential for scaling up to industrial production volumes. [hide] Scientific Board Andreas Bausch  TU Munich, Germany ► Peter Fischer  ETH Zurich, Switzerland ► Anne-Marie Hermansson  SIK, Sweden ► Martin Kroger  ETH Zurich, Germany/Switzerland ► Erik van der Linden  Wageningen UR, The Netherlands ► Niklas Loren  SIK, Sweden ► Leonard Sagis  Wageningen UR, The Netherlands ► Erich Windhab  ETH Zurich, Switzerland ► Klaas-Jan Zuidam  Unilever, The Netherlands ► Scientific Stuff Manuela Duxenneuner  ETH Zurich, Switzerland ► Sophia Fransson  SIK, Sweden ► Nam-Phuong Humblet-Hua  Wageningen UR, The Netherlands ► Joeska Husny  ETH Zurich, Australia/Switzerland ► Orit Peleg  ETH Zurich, Israel/Switzerland ► Cyrille Vezy  TU Munich, Germany ► Varvara Mitropoulos  ETH Zurich, Switzerland ► Associated Scientists
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neurofilament hydrogels EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 36 (2007) 661 ► SG Bolder, LMC Sagis, P Venema, E van der Linden, Effect of stirring and seeding on whey protein fibril formation JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 55 (2007) 5661 ► M Schonhoff, V Ball, AR Bausch, C Dejugnat, N Delorme, K Glinel, RV Klitzing, R Steitz, Hydration and internal properties of polyelectrolyte multilayers COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS 303 (2007) 14 ► P Fischer, A Eugster, EJ Windhab, M Schuleit, Predictive stress tests to study the influence of processing procedures on long term stability of supersaturated pharmaceutical o/w creams INTERNATIONAL JOURNAL OF PHARMACEUTICS 339 (2007) 189 ► KD Hermanson, D Huemmerich, T Scheibel, AR Bausch, Engineered microcapsules fabricated from reconstituted spider silk ADVANCED MATERIALS 19 (2007) 1810 ► K Feigl, D Megias-Alguacil, P Fischer, EJ Windhab, Simulation and experiments of droplet deformation and orientation in simple shear flow with surfactants CHEMICAL ENGINEERING SCIENCE 62 (2007) 3242 ► C Mohrdieck, F Dalmas, E Arzt, R Tharmann, MMAE Claessens, AR Bausch, A Roth, E Sackmann, CHJ Schmitz, J Curtis, W Roos, S Schulz, K Uhrig, JP Spatz, Biomimetic models of the actin cytoskeleton SMALL 3 (2007) 1015 ► M Colangeli, IV Karlin, M Kroger, From hyperbolic regularization to exact hydrodynamics for linearized Grad's equations PHYSICAL REVIEW E 75 (2007) 051204 ► SG Bolder, AJ Vasbinder, LMC Sagis, E van der Linden, Heat-induced whey protein isolate fibrils: Conversion, hydrolysis, and disulphide bond formation INTERNATIONAL DAIRY JOURNAL 17 (2007) 846 ► MA Pollard, R Kelly, C Wahl, P Fischer, E Windhab, B Eder, R Amado, Investigation of equilibrium solubility of a carob galactomannan FOOD HYDROCOLLOIDS 21 (2007) 683 ► L van den Berg, T van Vliet, E van der Linden, MAJS van Boekel, F van de Velde, Breakdown properties and sensory perception of whey proteins/polysaccharide mixed gels as a function of microstructure FOOD HYDROCOLLOIDS 21 (2007) 961 ► O Peleg, M Kroger, I Hecht, Y Rabin, Filamentous networks in phase-separating two-dimensional gels EPL 77 (2007) 58007 ► SG Bolder, LMC Sagis, P Venema, E van der Linden, Thioflavin T and birefringence assays to determine the conversion of proteins into fibrils LANGMUIR 23 (2007) 4144 ► S Shanbhag, M Kroger, Primitive path networks generated by annealing and geometrical methods: Insights into differences MACROMOLECULES 40 (2007) 2897 ► PA Neff, BK Wunderlich, R von Klitzing, AR Bausch, Formation and dielectric properties of polyelectrolyte multilayers studied by a silicon-on-insulator based thin film resistor LANGMUIR 23 (2007) 4048 ► LMC Sagis, Nonequilibrium thermodynamic model of water-in-water emulsions JOURNAL OF PHYSICAL CHEMISTRY C 111 (2007) 3139 ► K Mohlin, N Loren, M Nyden, Water pores in alkyl ketene dimer (AKD) dispersions studied by NMR diffusometry and optical microscopy COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS 297 (2007) 114 ► O Lieleg, MMAE Claessens, C Heussinger, E Frey, AR Bausch, Mechanics of bundled semiflexible polymer networks BIOPHYSICAL JOURNAL (2007Suppl.S) 139A ► M Bathe, MMAE Claessen, C Heussinger, AR Bausch, E Frey, F-actin bundle mechanical properties are sensitively mediated by actin-binding proteins and bundle dimensions BIOPHYSICAL JOURNAL (2007Suppl.S) 175A ► R Tharmann, MMAE Claessens, AR Bausch, Viscoelasticity of isotropically cross-linked actin networks PHYSICAL REVIEW LETTERS 98 (2007) 088103 ► LMC Sagis, Fluctuations of permeable interfaces in water-in-water emulsions PHYSICAL REVIEW LETTERS 98 (2007) 066105 ► R Nisslert, M Kvarnstrom, N Loren, M Nyden, M Rudemo, Identification of the three-dimensional gel microstructure from transmission electron micrographs JOURNAL OF MICROSCOPY-OXFORD 225 (2007) 10 ► J Brink, M Langton, M Stading, AM Hermansson, Simultaneous analysis of the structural and mechanical changes during large deformation of whey protein isolate/gelatin gels at the macro and micro levels FOOD HYDROCOLLOIDS 21 (2007) 409 ► L van den Berg, T van Vliet, E van der Linden, MAJS van Boekel, F van de Velde, Serum release: The hidden quality in fracturing composites FOOD HYDROCOLLOIDS 21 (2007) 420 ► C Lofgren, AM Hermansson, Synergistic rheological behaviour of mixed HM/LM pectin gels FOOD HYDROCOLLOIDS 21 (2007) 480 ►	login name password
Selected conferences (co-)organized by project members 8th World Congress on Computational Mechanics WCCM8 2008 30 June - 5 July 2007, Venice, Italy ► XVth International Workshop on Numerical Methods for non-Newtonian Flows 6-10 August 2007, Rhodes, Greece ► Structure Dynamics in Soft Condensed Matter (EUCHEM conference) 20-22 August 2007, Fiskebackskil, Sweden ►

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